KIAA1012

Protein TRS85 homolog is a protein that in humans is encoded by the KIAA1012 gene.[5][6][7]

TRAPPC8
Identifiers
Aliases	TRAPPC8, GSG1, HsT2706, KIAA1012, TRS85, trafficking protein particle complex 8
External IDs	OMIM: 614136 MGI: 2443008 HomoloGene: 40993 GeneCards: TRAPPC8
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18q12.1 Start 31,829,180 bp[1] End 31,953,136 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 A2 Start 20,817,223 bp[2] End 20,896,093 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • Rab guanyl-nucleotide exchange factor activity Cellular component • pre-autophagosomal structure • cytoplasmic vesicle • TRAPPIII protein complex • Golgi apparatus • cytosol • TRAPP complex Biological process • protein localization to pre-autophagosomal structure • autophagy of peroxisome • cytoplasm to vacuole transport by the Cvt pathway • autophagy of nucleus • ER to Golgi vesicle-mediated transport • vesicle-mediated transport • Golgi organization • autophagosome assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	22878	75964
Ensembl	ENSG00000153339	ENSMUSG00000033382
UniProt	Q9Y2L5	n/a
RefSeq (mRNA)	NM_014939	NM_029491 NM_177038 NM_001361188 NM_001379370
RefSeq (protein)	NP_055754	n/a
Location (UCSC)	Chr 18: 31.83 – 31.95 Mb	Chr 18: 20.82 – 20.9 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000153339 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000033382 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
6. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
7. "Entrez Gene: KIAA1012 KIAA1012".

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gavin AC, Bösche M, Krause R, et al. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. Bibcode:2002Natur.415..141G. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
• Sacher M, Barrowman J, Schieltz D, et al. (2000). "Identification and characterization of five new subunits of TRAPP". Eur. J. Cell Biol. 79 (2): 71–80. doi:10.1078/S0171-9335(04)70009-6. PMID 10727015.