KIAA0368

Proteasome-associated protein ECM29 homolog is a protein that in humans is encoded by the KIAA0368 gene.[5][6][7]

ECPAS
Identifiers
Aliases	ECPAS, ECM29, Ecm29 proteasome adaptor and scaffold, KIAA0368
External IDs	OMIM: 616694 MGI: 2140220 HomoloGene: 6056 GeneCards: ECPAS
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q31.3 Start 111,360,692 bp[1] End 111,484,745 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 B3 Start 58,798,911 bp[2] End 58,912,749 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • GO:0032947 molecular adaptor activity • proteasome binding Cellular component • cytoplasm • multivesicular body • endosome • late endosome • centrosome • membrane • endocytic vesicle • microtubule organizing center • trans-Golgi network • early endosome • endoplasmic reticulum • proteasome complex • COPII-coated ER to Golgi transport vesicle • cytoskeleton • cell nucleus • endoplasmic reticulum-Golgi intermediate compartment • cytoplasmic vesicle Biological process • ubiquitin-dependent ERAD pathway • proteasome assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23392	230249
Ensembl	ENSG00000136813	ENSMUSG00000050812
UniProt	Q5VYK3	Q6PDI5
RefSeq (mRNA)	NM_001080398 NM_001363756 NM_001364929 NM_001364930 NM_001364931	NM_172381 NM_001355696 NM_001355697
RefSeq (protein)	NP_001073867 NP_001350685 NP_001351858 NP_001351859 NP_001351860	NP_759013 NP_001342625 NP_001342626
Location (UCSC)	Chr 9: 111.36 – 111.48 Mb	Chr 4: 58.8 – 58.91 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000136813 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000050812 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Sep 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
6. Gorbea C, Goellner GM, Teter K, Holmes RK, Rechsteiner M (Dec 2004). "Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles". J Biol Chem. 279 (52): 54849–61. doi:10.1074/jbc.M410444200. PMID 15496406.
7. "Entrez Gene: KIAA0368 KIAA0368".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. S2CID 11683986.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.