Probable ribosome biogenesis protein RLP24

Probable ribosome biogenesis protein RLP24 is a protein that in humans is encoded by the RSL24D1 gene.[5][6][7]

RSL24D1
Identifiers
Aliases	RSL24D1, C15orf15, HRP-L30-iso, L30, RLP24, RPL24, RPL24L, TVAS3, ribosomal L24 domain containing 1
External IDs	OMIM: 613262 MGI: 2681840 HomoloGene: 9462 GeneCards: RSL24D1
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q21.3 Start 55,180,806 bp[1] End 55,197,049 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 D Start 73,113,426 bp[2] End 73,123,333 bp[2]
Gene ontology Molecular function • structural constituent of ribosome • GO:0001948 protein binding • RNA binding Cellular component • cytosolic large ribosomal subunit • ribosome • nucleolus • intracellular • cell nucleus Biological process • assembly of large subunit precursor of preribosome • protein biosynthesis • ribosomal large subunit assembly • ribosome biogenesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51187	225215
Ensembl	ENSG00000137876	ENSMUSG00000032215
UniProt	Q9UHA3	Q99L28
RefSeq (mRNA)	NM_016304	NM_198609
RefSeq (protein)	NP_057388	NP_941011
Location (UCSC)	Chr 15: 55.18 – 55.2 Mb	Chr 9: 73.11 – 73.12 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals.[7]

References

1. GRCh38: Ensembl release 89: ENSG00000137876 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032215 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Saveanu C, Namane A, Gleizes PE, Lebreton A, Rousselle JC, Noaillac-Depeyre J, Gas N, Jacquier A, Fromont-Racine M (Jun 2003). "Sequential protein association with nascent 60S ribosomal particles". Mol Cell Biol. 23 (13): 4449–60. doi:10.1128/MCB.23.13.4449-4460.2003. PMC 164837. PMID 12808088.
6. Saveanu C, Bienvenu D, Namane A, Gleizes PE, Gas N, Jacquier A, Fromont-Racine M (Nov 2001). "Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps". EMBO J. 20 (22): 6475–84. doi:10.1093/emboj/20.22.6475. PMC 125736. PMID 11707418.
7. "Entrez Gene: C15orf15 chromosome 15 open reading frame 15".

External links

• Human RPL24 genome location and RPL24 gene details page in the UCSC Genome Browser.
• Human RSL24D1 genome location and RSL24D1 gene details page in the UCSC Genome Browser.

Further reading

• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.