RRP15

RRP15-like protein is a protein that in humans is encoded by the RRP15 gene.[5][6]

RRP15
Identifiers
Aliases	RRP15, KIAA0507, CGI-115, ribosomal RNA processing 15 homolog
External IDs	OMIM: 611193 MGI: 1914473 HomoloGene: 32293 GeneCards: RRP15
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q41 Start 218,285,293 bp[1] End 218,337,983 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 H5 Start 186,720,978 bp[2] End 186,749,358 bp[2]
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51018	67223
Ensembl	ENSG00000067533	ENSMUSG00000001305
UniProt	Q9Y3B9	Q9CYX7
RefSeq (mRNA)	NM_016052	NM_026041
RefSeq (protein)	NP_057136	NP_080317
Location (UCSC)	Chr 1: 218.29 – 218.34 Mb	Chr 1: 186.72 – 186.75 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit.[6]

References

1. GRCh38: Ensembl release 89: ENSG00000067533 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000001305 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. De Marchis ML, Giorgi A, Schinina ME, Bozzoni I, Fatica A (Mar 2005). "Rrp15p, a novel component of pre-ribosomal particles required for 60S ribosome subunit maturation". RNA. 11 (4): 495–502. doi:10.1261/rna.7200205. PMC 1370738. PMID 15769876.
6. "Entrez Gene: RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)".

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
• Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
• Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.