Trestolone enanthate

Trestolone enanthate, also known as 7α-methyl-19-nortestosterone 17β-enanthate (MENT enanthate), is an androgen and anabolic steroid (AAS) and progestogen which was never marketed.[1][2] It is an androgen ester; specifically, it is the C17β enanthate (heptanoate) ester of trestolone (7α-methylestr-4-en-17β-ol-3-one).[2] Trestolone enanthate has low affinity for sex hormone-binding globulin (SHBG), similarly to testosterone enanthate.[1]

Trestolone enanthate

Clinical data
Other names	Trestolone 17β-enanthate; MENT enanthate; 7α-Methyl-19-nortestosterone 17β-enanthate; 7α-Methylestr-4-en-17β-ol-3-one 17β-enanthate
Pregnancy category	AU: D / X -->
Drug class	Androgen; Anabolic steroid; Androgen ester
Identifiers
IUPAC name (7R,8R,9S,10R,13S,14S,17S)-7,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl heptanoate
CAS Number	81005-56-3
Chemical and physical data
Formula	C26H40O3
Molar mass	400.603 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CCCCCCC(O[C@]1(CC[C@]2([C@@]3([C@@H](CC4=CC(CC[C@@]4([C@]3(CC[C@@]21C)[H])[H])=O)C)[H])[H])[H])=O
InChI InChI=1S/C26H40O3/c2+4+8+16+32+64+128(336)1+1(2)2+25(27)2+8+8(18)21(25)13-14-26(22,23)3/h16-17,20-23,25H,4-15H2,1-3H3/t17-,20+,21-,22+,23+,25-,26+/m1/s1 Key:YHLLSSBURKVUEG-YFGHHJRWSA-N

See also

• List of androgen esters § Esters of other synthetic AAS

References

1. Cunningham GR, Tindall DJ, Lobl TJ, Campbell JA, Means AR (September 1981). "Steroid structural requirements for high affinity binding to human sex steroid binding protein (SBP)". Steroids. 38 (3): 243–62. doi:10.1016/0039-128X(81)90061-1. PMID 7197818. S2CID 2702353.
2. Bursi R, Grootenhuis A, van der Louw J, Verhagen J, de Gooyer M, Jacobs P, Leysen D (March 2003). "Structure-activity relationship study of human liver microsomes-catalyzed hydrolysis rate of ester prodrugs of MENT by comparative molecular field analysis (CoMFA)". Steroids. 68 (3): 213–220. doi:10.1016/S0039-128X(02)00186-1. PMID 12628684. S2CID 32309966.