Felbinac

Felbinac (INN, or biphenylylacetic acid) is a topical medicine, belonging to the family of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation and arthritis. It is an active metabolite of fenbufen.[1]

Felbinac

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Topical
ATC code	M02AA08 (WHO)
Legal status
Legal status	UK: P (Pharmacy medicines)
Identifiers
IUPAC name biphenyl-4-ylacetic acid
CAS Number	5728-52-9
PubChem CID	3332
DrugBank	DB07477
ChemSpider	3215
UNII	94WNJ5U8L7
KEGG	D01675
ChEBI	CHEBI:31597
ChEMBL	ChEMBL413965
CompTox Dashboard (EPA)	DTXSID0045389
ECHA InfoCard	100.024.758
Chemical and physical data
Formula	C14H12O2
Molar mass	212.248 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=C(O)Cc1ccc(cc1)c2ccccc2
InChI InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N
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See also

• The isopropyl acid is called Biprofen (cf Flurbiprofen) and is used to prepare Bifepramide.
• The α-ethyl acid is called Xenbucin, this in turn is used to make Xenthiorate.
• Xenyhexenic Acid
• Fluenetil

Footnotes

1. Kohler C, Tolman E, Wooding W, Ellenbogen L (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung. 30 (4A): 702–707. PMID 6254545.

References

• The Merck Index, 12th Edition. 3989
• Description of Felbinac on Tiscali