T-1123

T-1123 is a carbamate-based acetylcholinesterase inhibitor. It was investigated as a chemical warfare agent starting in 1940. It does not go through the blood-brain barrier due to the charge on quaternary nitrogen. The antidote is atropine.[1] T-1123 is a quaternary ammonium ion. A phenyl carbamate ester is bonded in the meta position to the nitrogen on a diethylmethyl amine.

T-1123

Names
IUPAC name N,N-diethyl-N-methyl-3-[(methylcarbamoyl)oxy]anilinium chloride
Other names AR-16, TL-1217, TL-1299
Identifiers
CAS Number	64046-12-4
3D model (JSmol)	Interactive image
ChemSpider	42375
PubChem CID	46574
CompTox Dashboard (EPA)	DTXSID40982154
InChI InChI=1S/C13H20N2O2.ClH/c1-5-15(4,6-2)11-8-7-9-12(10-11)17-13(16)14-3;/h7-10H,5-6H2,1-4H3;1H Key: JLNMGRFEXZJGFZ-UHFFFAOYSA-N
SMILES CC[N+](C)(CC)c1cccc(c1)OC(=O)NC.[Cl-]
Properties
Chemical formula	C13H21ClN2O2
Molar mass	272.77 g·mol^−1
Related compounds
Related compounds	Neostigmine Miotine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

• EA-3990
• EA-4056
• Miotine
• Neostigmine
• TL-1238

References

1. Gupta, Ramesh C. (2015). Handbook of Toxicology of Chemical Warfare Agents. Academic Press. pp. 338–339. ISBN 9780128004944.

Extra reading

• Robinson, J. P. (1971). The Problem of Chemical and Biological Warfare: The rise of CB weapons. Almqvist & Wiksell.