CD320

CD320 (cluster of differentiation 320) is a human gene.[5]

CD320
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4ZRP
Identifiers
Aliases	CD320, 8D6, 8D6A, TCBLR, CD320 molecule, TCN2R
External IDs	OMIM: 606475 MGI: 1860083 HomoloGene: 9573 GeneCards: CD320
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.2 Start 8,302,127 bp[1] End 8,308,358 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 B1|17 17.98 cM Start 33,843,091 bp[2] End 33,849,774 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • cobalamin binding • growth factor activity • GO:0102023, GO:0015235 ATPase-coupled vitamin B12 transmembrane transporter activity • GO:0001948 protein binding • calcium ion binding • metal ion binding Cellular component • integral component of membrane • endosome membrane • endoplasmic reticulum • membrane • extracellular exosome • integral component of plasma membrane • cell membrane Biological process • cobalamin metabolic process • regulation of vitamin metabolic process • cobalamin transport • positive regulation of B cell proliferation • B cell costimulation • regulation of receptor activity • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51293	54219
Ensembl	ENSG00000167775	ENSMUSG00000002308
UniProt	Q9NPF0	Q9Z1P5
RefSeq (mRNA)	NM_016579 NM_001165895	NM_019421 NM_001305169
RefSeq (protein)	NP_001159367 NP_057663	NP_001292098 NP_062294
Location (UCSC)	Chr 19: 8.3 – 8.31 Mb	Chr 17: 33.84 – 33.85 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000167775 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000002308 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: CD320 CD320 molecule".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Li L, Zhang X, Kovacic S, et al. (2000). "Identification of a Human Follicular Dendritic Cell Molecule That Stimulates Germinal Center B Cell Growth". J. Exp. Med. 191 (6): 1077–84. doi:10.1084/jem.191.6.1077. PMC 2193124. PMID 10727470.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Acierno JS, Kennedy JC, Falardeau JL, et al. (2001). "A physical and transcript map of the MCOLN1 gene region on human chromosome 19p13.3-p13.2". Genomics. 73 (2): 203–10. doi:10.1006/geno.2001.6526. PMID 11318610.
• Zhang X, Li L, Jung J, et al. (2001). "The distinct roles of T cell-derived cytokines and a novel follicular dendritic cell-signaling molecule 8D6 in germinal center-B cell differentiation". J. Immunol. 167 (1): 49–56. doi:10.4049/jimmunol.167.1.49. PMID 11418631.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• CD320+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• Human CD320 genome location and CD320 gene details page in the UCSC Genome Browser.
• Overview of all the structural information available in the PDB for UniProt: Q9NPF0 (Human CD320 antigen) at the PDBe-KB.