Thiopropazate

Thiopropazate (Artalan, Dartal, Dartalan, Dartan) is a typical antipsychotic of the phenothiazine class.[1] It is a prodrug to perphenazine.

Thiopropazate

Clinical data
Trade names	Artalan, Dartal, Dartalan, Dartan
ATC code	N05AB05 (WHO)
Identifiers
IUPAC name 2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethyl acetate
CAS Number	84-06-0
PubChem CID	6762
ChemSpider	6504
UNII	0JFY081Q2X
KEGG	D09216
ChEBI	CHEBI:59119
CompTox Dashboard (EPA)	DTXSID6023654
ECHA InfoCard	100.001.376
Chemical and physical data
Formula	C23H28ClN3O2S
Molar mass	446.01 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC(=O)OCCN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl
InChI InChI=1S/C23H28ClN3O2S/c1-18(28)29-16-15-26-13-11-25(12-14-26)9-4-10-27-20-5-2-3-6-22(20)30-23-8-7-19(24)17-21(23)27/h2-3,5-8,17H,4,9-16H2,1H3 Key:AIUHRQHVWSUTGJ-UHFFFAOYSA-N
(verify)

Thiopropazate is manufactured by Searle (US, UK) & Boehringer Mannheim (Germany)[2] Thiopropazate is sold by Chembase, AAA Chemistry, ZINC, AKos Consulting & Solutions, Boc Sciences, ChemFrog, and ChemMol[3]

See also

• Typical antipsychotic
• Phenothiazine

References

1. Dictionary of organic compounds. London: Chapman & Hall. 1996. p. 5148. ISBN 0-412-54090-8.
2. Pharmaceutical Manufacturing Encyclopedia p. 3209
3. https://pubchem.ncbi.nlm.nih.gov/compound/thiopropazate#section=Top