GPR115

Probable G-protein coupled receptor 115 is a protein that in humans is encoded by the GPR115 gene.[5][6]

ADGRF4
Identifiers
Aliases	ADGRF4, PGR18, GPR115, adhesion G protein-coupled receptor F4
External IDs	OMIM: 614268 MGI: 1925499 HomoloGene: 51953 GeneCards: ADGRF4
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p12.3 Start 47,685,864 bp[1] End 47,722,021 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 B3 Start 42,656,891 bp[2] End 42,692,284 bp[2]
Gene ontology Molecular function • G-protein coupled receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • integral component of membrane • membrane Biological process • G-protein coupled receptor signaling pathway • cell surface receptor signaling pathway • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	221393	78249
Ensembl	ENSG00000153294	ENSMUSG00000023918
UniProt	Q8IZF3	Q9D2L6
RefSeq (mRNA)	NM_153838 NM_001347855	NM_001289499 NM_001289500 NM_001289501 NM_030067
RefSeq (protein)	NP_001334784 NP_722580	NP_001276428 NP_001276429 NP_001276430 NP_084343
Location (UCSC)	Chr 6: 47.69 – 47.72 Mb	Chr 17: 42.66 – 42.69 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000153294 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000023918 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. S2CID 7449692.
6. "Entrez Gene: GPR115 G protein-coupled receptor 115".

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.