TAS2R19

Taste receptor type 2 member 19 is a protein that in humans is encoded by the TAS2R19 gene.[3] It seems to be involved in the perception of salt and bitter tastes.

TAS2R19
Identifiers
Aliases	TAS2R19, MSTP058, T2R19, T2R23, T2R48, TAS2R23, TAS2R48, taste 2 receptor member 19
External IDs	OMIM: 613961 HomoloGene: 89250 GeneCards: TAS2R19
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.2 Start 11,021,619 bp[1] End 11,022,620 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • bitter taste receptor activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • detection of chemical stimulus involved in sensory perception of bitter taste • signal transduction • response to stimulus • sensory perception of taste • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	259294	n/a
Ensembl	ENSG00000278307 ENSG00000263028 ENSG00000212124	n/a
UniProt	P59542	n/a
RefSeq (mRNA)	NM_176888	n/a
RefSeq (protein)	NP_795369	n/a
Location (UCSC)	Chr 12: 11.02 – 11.02 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

See also

• Taste receptor

References

1. ENSG00000263028, ENSG00000212124 GRCh38: Ensembl release 89: ENSG00000278307, ENSG00000263028, ENSG00000212124 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: TAS2R19 taste receptor, type 2, member 19".

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
• Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat. Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.