GPR139

Probable G-protein coupled receptor 139 is a protein that in humans is encoded by the GPR139 gene.[5][6]

GPR139
Identifiers
Aliases	GPR139, GPRg1, PGR3, G protein-coupled receptor 139
External IDs	OMIM: 618448 MGI: 2685341 HomoloGene: 45860 GeneCards: GPR139
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p12.3 Start 20,031,485 bp[1] End 20,073,917 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F2 Start 119,140,747 bp[2] End 119,184,603 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • protein dimerization activity • signal transducer activity • neuropeptide receptor activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • G-protein coupled receptor signaling pathway • phospholipase C-activating G-protein coupled receptor signaling pathway • neuropeptide signaling pathway • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	124274	209776
Ensembl	ENSG00000180269	ENSMUSG00000066197
UniProt	Q6DWJ6	Q80UC8
RefSeq (mRNA)	NM_001002911 NM_001318483	NM_001024138
RefSeq (protein)	NP_001002911 NP_001305412	NP_001019309
Location (UCSC)	Chr 16: 20.03 – 20.07 Mb	Chr 7: 119.14 – 119.18 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000180269 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000066197 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA (Apr 2003). "The G protein-coupled receptor repertoires of human and mouse". Proc Natl Acad Sci U S A. 100 (8): 4903–8. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
6. "Entrez Gene: GPR139 G protein-coupled receptor 139".

Biochem Biophys Res Commun. 2003 May 23;305(1):67-71. Novel human G-protein-coupled receptors. Vanti WB1, Nguyen T, Cheng R, Lynch KR, George SR, O'Dowd BF.

Further reading

• Ottolenghi C, Fellous M, Barbieri M, McElreavey K (2002). "Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination". Genomics. 79 (3): 333–43. doi:10.1006/geno.2002.6711. PMID 11863363.
• Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392.
• Gloriam DE, Schiöth HB, Fredriksson R (2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim. Biophys. Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626.
• Matsuo A, Matsumoto S, Nagano M, et al. (2005). "Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system". Biochem. Biophys. Res. Commun. 331 (1): 363–9. doi:10.1016/j.bbrc.2005.03.174. PMID 15845401.