FOXJ2

Forkhead box protein J2 is a protein that in humans is encoded by the FOXJ2 gene.[5][6][7]

FOXJ2
Identifiers
Aliases	FOXJ2, FHX, forkhead box J2
External IDs	MGI: 1926805 HomoloGene: 10187 GeneCards: FOXJ2
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.31 Start 8,032,716 bp[1] End 8,055,517 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 F1-F2 Start 122,819,914 bp[2] End 122,845,366 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • sequence-specific DNA binding • DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001948 protein binding • identical protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • cell nucleus • fibrillar center Biological process • positive regulation of transcription, DNA-templated • regulation of transcription, DNA-templated • transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter • anatomical structure morphogenesis • cell differentiation • negative regulation of angiogenesis • negative regulation of blood vessel endothelial cell differentiation • positive regulation of vascular smooth muscle cell proliferation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55810	60611
Ensembl	ENSG00000065970	ENSMUSG00000003154
UniProt	Q9P0K8	Q9ES18
RefSeq (mRNA)	NM_018416	NM_021899
RefSeq (protein)	NP_060886	NP_068699
Location (UCSC)	Chr 12: 8.03 – 8.06 Mb	Chr 6: 122.82 – 122.85 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000065970 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000003154 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Perez-Sanchez C, Gomez-Ferreria MA, de La Fuente CA, Granadino B, Velasco G, Esteban-Gamboa A, Rey-Campos J (Jun 2000). "FHX, a novel fork head factor with a dual DNA binding specificity". J Biol Chem. 275 (17): 12909–16. doi:10.1074/jbc.275.17.12909. PMID 10777590.
6. Perez-Sanchez C, Arias-de-la-Fuente C, Gomez-Ferreria MA, Granadino B, Rey-Campos J (Sep 2000). "FHX.L and FHX.S, two isoforms of the human fork-head factor FHX (FOXJ2) with differential activity". J Mol Biol. 301 (4): 795–806. doi:10.1006/jmbi.2000.3999. PMID 10966786.
7. "Entrez Gene: FOXJ2 forkhead box J2".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gómez-Ferrería MA, Rey-Campos J (2003). "Functional domains of FOXJ2". J. Mol. Biol. 329 (4): 631–44. doi:10.1016/S0022-2836(03)00524-2. PMID 12787665.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.