PHF3

PHD finger protein 3 is a protein that in humans is encoded by the PHF3 gene.[5][6]

PHF3
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2DME
Identifiers
Aliases	PHF3, PHD finger protein 3
External IDs	OMIM: 607789 MGI: 2446126 HomoloGene: 9040 GeneCards: PHF3
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q12 Start 63,635,820 bp[1] End 63,779,336 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 A5 Start 30,802,339 bp[2] End 30,873,921 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • metal ion binding • molecular function Cellular component • cellular component Biological process • multicellular organism development • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23469	213109
Ensembl	ENSG00000118482	ENSMUSG00000048874
UniProt	Q92576	n/a
RefSeq (mRNA)	NM_001290259 NM_001290260 NM_015153 NM_001370348 NM_001370349 NM_001370350	NM_001081080 NM_025871
RefSeq (protein)	NP_001277188 NP_001277189 NP_055968 NP_001357277 NP_001357278 NP_001357279	n/a
Location (UCSC)	Chr 6: 63.64 – 63.78 Mb	Chr 1: 30.8 – 30.87 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000118482 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000048874 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Fischer U, Struss AK, Hemmer D, Michel A, Henn W, Steudel WI, Meese E (Mar 2002). "PHF3 expression is frequently reduced in glioma". Cytogenet Cell Genet. 94 (3–4): 131–6. doi:10.1159/000048804. PMID 11856869. S2CID 44396216.
6. "Entrez Gene: PHF3 PHD finger protein 3".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
• Struss AK, Romeike BF, Munnia A, et al. (2001). "PHF3-specific antibody responses in over 60% of patients with glioblastoma multiforme". Oncogene. 20 (31): 4107–14. doi:10.1038/sj.onc.1204552. PMID 11464277.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Pallasch CP, Struss AK, Munnia A, et al. (2005). "Autoantibodies against GLEA2 and PHF3 in glioblastoma: tumor-associated autoantibodies correlated with prolonged survival". Int. J. Cancer. 117 (3): 456–9. doi:10.1002/ijc.20929. PMID 15906353. S2CID 32083805.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

• PHF3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.