OR10C1

Olfactory receptor 10C1 is a protein that in humans is encoded by the OR10C1 gene.[4]

OR10C1
Identifiers
Aliases	OR10C1, OR10C1P, OR10C2, OR6-31, hs6M1-17, olfactory receptor family 10 subfamily C member 1 (gene/pseudogene), olfactory receptor family 10 subfamily C member 1
External IDs	MGI: 2177478 HomoloGene: 71990 GeneCards: OR10C1
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.1 Start 29,439,306 bp[1] End 29,440,977 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	442194	258506
Ensembl	ENSG00000230505 ENSG00000229412 ENSG00000206474 ENSG00000220550 ENSG00000232397 ENSG00000204689 ENSG00000224234 ENSG00000235441	ENSMUSG00000049561
UniProt	Q96KK4	Q8VFE2
RefSeq (mRNA)	NM_013941	NM_146513
RefSeq (protein)	NP_039229	NP_666724
Location (UCSC)	Chr 6: 29.44 – 29.44 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. ENSG00000229412, ENSG00000206474, ENSG00000220550, ENSG00000232397, ENSG00000204689, ENSG00000224234, ENSG00000235441 GRCh38: Ensembl release 89: ENSG00000230505, ENSG00000229412, ENSG00000206474, ENSG00000220550, ENSG00000232397, ENSG00000204689, ENSG00000224234, ENSG00000235441 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR10C1 olfactory receptor, family 10, subfamily C, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Volz A, Ehlers A, Younger R, et al. (2003). "Complex transcription and splicing of odorant receptor genes". J. Biol. Chem. 278 (22): 19691–701. doi:10.1074/jbc.M212424200. PMID 12637542.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR10C1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.