OR2AK2

Olfactory receptor 2AK2 is a protein that in humans is encoded by the OR2AK2 gene.[5]

OR2AK2
Identifiers
Aliases	OR2AK2, OR1-47, OR2AK1P, olfactory receptor family 2 subfamily AK member 2
External IDs	MGI: 3030150 HomoloGene: 133825 GeneCards: OR2AK2
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q44 Start 247,965,233 bp[1] End 247,966,386 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B1.3 Start 58,752,734 bp[2] End 58,759,671 bp[2]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	391191	258064
Ensembl	ENSG00000187080	ENSMUSG00000107677
UniProt	Q8NG84	A0A0N4SVP2
RefSeq (mRNA)	NM_001004491	NM_001011818
RefSeq (protein)	NP_001004491	NP_001011818
Location (UCSC)	Chr 1: 247.97 – 247.97 Mb	Chr 11: 58.75 – 58.76 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000187080 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000107677 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR2AK2 olfactory receptor, family 2, subfamily AK, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR2AK2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.