OR5AC2

Olfactory receptor 5AC2 is a protein that in humans is encoded by the OR5AC2 gene.[4]

OR5AC2
Identifiers
Aliases	OR5AC2, HSA1, olfactory receptor family 5 subfamily AC member 2
External IDs	MGI: 3030032 HomoloGene: 51800 GeneCards: OR5AC2
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q11.2 Start 98,087,173 bp[1] End 98,088,102 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • odorant binding • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	81050	258036
Ensembl	ENSG00000196578	ENSMUSG00000052537
UniProt	Q9NZP5	Q7TS40
RefSeq (mRNA)	NM_054106	NM_001011808
RefSeq (protein)	NP_473447	NP_001011808
Location (UCSC)	Chr 3: 98.09 – 98.09 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196578 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR5AC2 olfactory receptor, family 5, subfamily AC, member 2".

Further reading

• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: Evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
• Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. doi:10.1038/nature04728. PMID 16641997.

External links

• OR5AC2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.