OR5F1

Olfactory receptor 5F1 is a protein that in humans is encoded by the OR5F1 gene.[3][4]

OR5F1
Identifiers
Aliases	OR5F1, OR11-10, olfactory receptor family 5 subfamily F member 1
External IDs	OMIM: 608492 HomoloGene: 130524 GeneCards: OR5F1
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 55,993,681 bp[1] End 55,994,625 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • odorant binding • signal transducer activity • olfactory receptor activity Cellular component • membrane • cell membrane • integral component of membrane Biological process • signal transduction • response to stimulus • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	338674	n/a
Ensembl	ENSG00000149133	n/a
UniProt	O95221	n/a
RefSeq (mRNA)	NM_003697	n/a
RefSeq (protein)	NP_003688	n/a
Location (UCSC)	Chr 11: 55.99 – 55.99 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000149133 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (Dec 1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077.
4. "Entrez Gene: OR5F1 olfactory receptor, family 5, subfamily F, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5F1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.