OR5AR1

Olfactory receptor 5AR1 is a protein that in humans is encoded by the OR5AR1 gene.[5]

OR5AR1
Identifiers
Aliases	OR5AR1, OR11-209, olfactory receptor family 5 subfamily AR member 1 (gene/pseudogene), olfactory receptor family 5 subfamily AR member 1
External IDs	MGI: 3030853 HomoloGene: 17464 GeneCards: OR5AR1
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 56,663,662 bp[1] End 56,664,687 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 D Start 85,839,621 bp[2] End 85,845,483 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • olfactory receptor activity • odorant binding • copper ion binding Cellular component • integral component of membrane • cell membrane • membrane • integral component of plasma membrane Biological process • response to stimulus • signal transduction • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway • detection of chemical stimulus involved in sensory perception Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	219493	259017
Ensembl	ENSG00000172459	ENSMUSG00000075208
UniProt	Q8NGP9	Q8VGS3
RefSeq (mRNA)	NM_001004730	NM_147015
RefSeq (protein)	NP_001004730	NP_667226
Location (UCSC)	Chr 11: 56.66 – 56.66 Mb	Chr 2: 85.84 – 85.85 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172459 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075208 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5AR1 olfactory receptor, family 5, subfamily AR, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5AR1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.