OR52I2

Olfactory receptor 52I2 is a protein that in humans is encoded by the OR52I2 gene.[4]

OR52I2
Identifiers
Aliases	OR52I2, OR11-12, OR52I1, olfactory receptor family 52 subfamily I member 2
External IDs	MGI: 3030390 HomoloGene: 17380 GeneCards: OR52I2
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11p15.4 Start 4,581,743 bp[1] End 4,593,340 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	143502	258749
Ensembl	ENSG00000226288	ENSMUSG00000073969
UniProt	Q8NH67	E9Q549
RefSeq (mRNA)	NM_001005170	NM_146754
RefSeq (protein)	NP_001005170	NP_666965
Location (UCSC)	Chr 11: 4.58 – 4.59 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000226288 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR52I2 olfactory receptor, family 52, subfamily I, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR52I2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.