OR2H1

Olfactory receptor 2H1 is a protein that in humans is encoded by the OR2H1 gene.[5]

OR2H1
Identifiers
Aliases	OR2H1, 6M1-16, HS6M1-16, OLFR42A-9004-14, OR2H6, OR2H8, OR6-2, dJ994E9.4, OLFR42A-9004.14/9026.2, olfactory receptor family 2 subfamily H member 1
External IDs	MGI: 2177474 HomoloGene: 72346 GeneCards: OR2H1
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.1 Start 29,457,181 bp[1] End 29,464,328 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 B1 Start 37,090,618 bp[2] End 37,098,278 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	26716	258470
Ensembl	ENSG00000206516 ENSG00000204688 ENSG00000224395 ENSG00000206471 ENSG00000229125 ENSG00000232984 ENSG00000229408 ENSG00000235132	ENSMUSG00000095377
UniProt	Q9GZK4	Q7TRL3
RefSeq (mRNA)	NM_030883 NM_001318014 NM_001318022	NM_182714
RefSeq (protein)	NP_001304943 NP_001304951 NP_112145	NP_874373
Location (UCSC)	Chr 6: 29.46 – 29.46 Mb	Chr 17: 37.09 – 37.1 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. ENSG00000204688, ENSG00000224395, ENSG00000206471, ENSG00000229125, ENSG00000232984, ENSG00000229408, ENSG00000235132 GRCh38: Ensembl release 89: ENSG00000206516, ENSG00000204688, ENSG00000224395, ENSG00000206471, ENSG00000229125, ENSG00000232984, ENSG00000229408, ENSG00000235132 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000095377 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR2H1 olfactory receptor, family 2, subfamily H, member 1".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Volz A, Ehlers A, Younger R, et al. (2003). "Complex transcription and splicing of odorant receptor genes". J. Biol. Chem. 278 (22): 19691–701. doi:10.1074/jbc.M212424200. PMID 12637542.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Santos PS, Kellermann T, Uchanska-Ziegler B, et al. (2010). "Genomic architecture of MHC-linked odorant receptor gene repertoires among 16 vertebrate species". Immunogenetics. 62 (9): 569–84. doi:10.1007/s00251-010-0468-6. PMID 20680261. S2CID 23003444.

External links

• OR2H1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.