OR4K14

Olfactory receptor 4K14 is a protein that in humans is encoded by the OR4K14 gene.[3]

OR4K14
Identifiers
Aliases	OR4K14, OR14-18, OR14-22, olfactory receptor family 4 subfamily K member 14
External IDs	HomoloGene: 128265 GeneCards: OR4K14
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q11.2 Start 20,014,143 bp[1] End 20,019,307 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • membrane • cell membrane • integral component of membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	122740	n/a
Ensembl	ENSG00000169484	n/a
UniProt	Q8NGD5	n/a
RefSeq (mRNA)	NM_001004712	n/a
RefSeq (protein)	NP_001004712	n/a
Location (UCSC)	Chr 14: 20.01 – 20.02 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000169484 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR4K14 olfactory receptor, family 4, subfamily K, member 14".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.145.6233. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4K14+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.