OR1I1

Olfactory receptor 1I1 is a protein that in humans is encoded by the OR1I1 gene.[4]

OR1I1
Identifiers
Aliases	OR1I1, OR19-20, OR1I1P, OR1I1Q, olfactory receptor family 1 subfamily I member 1
External IDs	MGI: 3031191 HomoloGene: 72920 GeneCards: OR1I1
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.12 Start 15,082,211 bp[1] End 15,092,970 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • transmembrane signaling receptor activity • olfactory receptor activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • response to stimulus • signal transduction • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	126370	257883
Ensembl	ENSG00000094661	ENSMUSG00000071185
UniProt	O60431	Q7TQU7
RefSeq (mRNA)	NM_001004713	NM_001011737
RefSeq (protein)	NP_001004713	NP_001011737
Location (UCSC)	Chr 19: 15.08 – 15.09 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000094661 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR1I1 olfactory receptor, family 1, subfamily I, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.

External links

• OR1I1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.