OR5K2

Olfactory receptor 5K2 is a protein that in humans is encoded by the OR5K2 gene.[5]

OR5K2
Identifiers
Aliases	OR5K2, OR3-9, olfactory receptor family 5 subfamily K member 2
External IDs	MGI: 3030011 HomoloGene: 121500 GeneCards: OR5K2
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q11.2 Start 98,497,604 bp[1] End 98,498,663 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C1.2 Start 58,870,955 bp[2] End 58,874,768 bp[2]
Gene ontology Molecular function • G-protein coupled receptor activity • odorant binding • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	402135	258998
Ensembl	ENSG00000231861	ENSMUSG00000063137
UniProt	Q8NHB8	E9Q7W1
RefSeq (mRNA)	NM_001004737	NM_146996
RefSeq (protein)	NP_001004737	NP_667207
Location (UCSC)	Chr 3: 98.5 – 98.5 Mb	Chr 16: 58.87 – 58.87 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000231861 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000063137 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5K2 olfactory receptor, family 5, subfamily K, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. doi:10.1038/nature04728. PMID 16641997.

External links

• OR5K2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.