OR4L1

Olfactory receptor 4L1 is a protein that in humans is encoded by the OR4L1 gene.[4]

OR4L1
Identifiers
Aliases	OR4L1, OR14-28, OR4L2P, olfactory receptor family 4 subfamily L member 1, olfactory receptor family 4 subfamily L member 1 (gene/pseudogene)
External IDs	MGI: 3030558 HomoloGene: 71986 GeneCards: OR4L1
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q11.2 Start 20,060,045 bp[1] End 20,060,983 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	122742	258485
Ensembl	ENSG00000176246	ENSMUSG00000096254
UniProt	Q8NH43	K7N5X7
RefSeq (mRNA)	NM_001004717	NM_146492
RefSeq (protein)	NP_001004717	NP_666703
Location (UCSC)	Chr 14: 20.06 – 20.06 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000176246 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR4L1 olfactory receptor, family 4, subfamily L, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4L1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.