OR8G2

Olfactory receptor 8G2 is a protein that in humans is encoded by the OR8G2 gene.[4][5]

OR8G2P
Identifiers
Aliases	OR8G2P, HSTPCR120, OR8G4, ORL206, ORL486, TPCR120, OR8G2, olfactory receptor family 8 subfamily G member 2, olfactory receptor family 8 subfamily G member 2 pseudogene
External IDs	MGI: 3030063 HomoloGene: 115513 GeneCards: OR8G2P
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q24.2 Start 124,224,732 bp[1] End 124,225,639 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • olfactory receptor activity • odorant binding Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	26492	258606
Ensembl	ENSG00000181214	ENSMUSG00000095390
UniProt	Q6IF36	Q8VFN5
RefSeq (mRNA)	NM_001291438	NM_146613
RefSeq (protein)	NP_001278367	NP_666824
Location (UCSC)	Chr 11: 124.22 – 124.23 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181214 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.
5. "Entrez Gene: OR8G2 olfactory receptor, family 8, subfamily G, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR8G2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.