OR8K5

Olfactory receptor 8K5 is a protein that in humans is encoded by the OR8K5 gene.[4]

OR8K5
Identifiers
Aliases	OR8K5, OR11-174, olfactory receptor family 8 subfamily K member 5
External IDs	MGI: 3030887 HomoloGene: 74197 GeneCards: OR8K5
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 56,159,394 bp[1] End 56,160,317 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • odorant binding • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	219453	257974
Ensembl	ENSG00000181752	ENSMUSG00000075192
UniProt	Q8NH50	L7MU59
RefSeq (mRNA)	NM_001004058	NM_001177857
RefSeq (protein)	NP_001004058	NP_001171328
Location (UCSC)	Chr 11: 56.16 – 56.16 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181752 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR8K5 olfactory receptor, family 8, subfamily K, member 5".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR8K5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.