OR4C11

Olfactory receptor 4C11 is a protein that in humans is encoded by the OR4C11 gene.[5]

OR4C11
Identifiers
Aliases	OR4C11, OR11-136, OR4C11P, olfactory receptor family 4 subfamily C member 11
External IDs	MGI: 3031035 HomoloGene: 81567 GeneCards: OR4C11
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q11 Start 55,602,360 bp[1] End 55,607,645 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 E1 Start 88,793,036 bp[2] End 88,796,827 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	219429	258897
Ensembl	ENSG00000172188	ENSMUSG00000059023
UniProt	Q6IEV9	Q8VGF5
RefSeq (mRNA)	NM_001004700	NM_146895
RefSeq (protein)	NP_001004700	NP_667106
Location (UCSC)	Chr 11: 55.6 – 55.61 Mb	Chr 2: 88.79 – 88.8 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172188 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059023 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR4C11 olfactory receptor, family 4, subfamily C, member 11".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4C11+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.